CORIN Recombinant Protein (OPCD02422)

Catalog No: OPCD02422

CORIN Recombinant Protein (OPCD02422) using SDS-PAGE

CORIN Recombinant Protein (OPCD02422) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gln334-Ser477
  Subcellular Location: Secreted. Cell membrane; Single-pass type II membrane prote
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: >95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Corin
• Gene Full Name: corin, serine peptidase
• Alias Symbols: atrial natriuretic peptide-converting enzyme;AV273130;Corin;L;low density lipoprotein receptor-related protein 4;low density lipoprotein-related protein 4;Lrp4;pro-ANP-converting enzyme.
• NCBI Gene Id: 53419
• Protein Name: Atrial natriuretic peptide-converting enzyme
• Description of Target: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.
• Uniprot ID: Q9Z319
• Protein Accession #: NP_001116228.1
• Nucleotide Accession #: NM_001122756.1
• Protein Size (# AA): Gln334~Ser477
• Molecular Weight: 26kDa