COQ7 Antibody (OACA07398)

Catalog No: OACA07398

Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100

Immunohistochemistry of paraffin-embedded human skeletal muscle at dilution 1:100

Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100

Immunohistochemistry of paraffin-embedded human skeletal muscle at dilution 1:100

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunohistochemistry
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human 5-demethoxyubiquinone hydroxylase, mitochondrial protein (37-217AA)
• Purification: Affinity Purified
• Preservative: 0.02% sodium azide
• Formulation: PBS with, 50% glycerol, pH7.3.
• Reference: [1]"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. Poustka A.Genome Res. 11:422-435(2001). [2]"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004). [3]"The sequence and analysis of duplication-rich human chromosome 16." Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. Pennacchio L.A.Nature 432:988-994(2004).

Target Info

• Gene Symbol: COQ7
• Gene Full Name: coenzyme Q7, hydroxylase
• Alias Symbols: 5-demethoxyubiquinone hydroxylase, mitochondrial;CAT5;CLK1;CLK-1;coenzyme Q biosynthesis protein 7 homolog;coenzyme Q7 homolog, ubiquinone;COQ10D8;COQ7 coenzyme Q, 7 homolog ubiquinone;DMQ hydroxylase;placental protein KG-20;timing protein clk-1 homolog;ubiquinone biosynthesis monooxygenase COQ7;ubiquinone biosynthesis protein COQ7 homolog.
• NCBI Gene Id: 10229
• Protein Name: 5-demethoxyubiquinone hydroxylase, mitochondrial
• Description of Target: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
• Uniprot ID: Q99807
• Protein Accession #: NP_001177912
• Nucleotide Accession #: NM_001190983