Catalog No: ARP52242_P050-Biotin
Size:100ul
Price: $434.00
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ARP52242_P050-Biotin
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COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)

Datasheets/ManualsPrintable datasheet for anti-COPS8 (ARP52242_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB, IHC
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human COPS8
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: TRMVLPRKPVAGALDVSFNKFIPLSEPAPVPPIPNEQQLARLTDYVAFLE
Concentration0.5 mg/ml
Blocking PeptideFor anti-COPS8 (ARP52242_P050-Biotin) antibody is Catalog # AAP52242 (Previous Catalog # AAPP44002)
Sample Type Confirmation

There is BioGPS gene expression data showing that COPS8 is expressed in HepG2

Subunit8
Publications

Pick, E. et al. The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain. PLoS One 7, e43980 (2012). WB, Bovine, Human, Rat, Horse, Rabbit, Guinea pig, Dog, Mouse 22956996

Gene SymbolCOPS8
Gene Full NameCOP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
Alias SymbolsCOP9, CSN8, SGN8
NCBI Gene Id10920
Protein NameCOP9 signalosome complex subunit 8
Description of TargetThe protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Uniprot IDQ99627
Protein Accession #NP_006701
Nucleotide Accession #NM_006710
Protein Size (# AA)209
Molecular Weight23kDa
Protein InteractionsUSHBP1; GPS1; cul1; WDR77; SRRT; COPS7A; VIM; COPS4; FBXO6; FBXW4; COPS5; vpr; IRF5; DDIT3; COPS2; COPS3; COPS6; PINK1; RFWD2; CUL4A; UBC; LRR1; DDA1; DDB2; DCUN1D1; VPRBP; CUL2; CUL3; CUL4B; CUL5; NEDD8; JUN; GFER; ERCC8; DDB1; CTNNB1; RAE1; COPS8; EIF3E
  1. What is the species homology for "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)"?

    This target may also be called "COP9, CSN8, SGN8" in publications.

  5. What is the shipping cost for "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "23kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "COPS8 Antibody - middle region : Biotin (ARP52242_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "COPS8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "COPS8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "COPS8"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "COPS8"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "COPS8"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "COPS8"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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