COLEC12 Antibody - middle region (ARP50285_P050)

Catalog No: ARP50285_P050

WB Suggested Anti-COLEC12 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Liver

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COLEC12
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-COLEC12 (ARP50285_P050) antibody is Catalog # AAP50285 (Previous Catalog # AAPS29007)
• Reference: Coombs,P.J., (2005) J. Biol. Chem. 280 (24), 22993-22999

Target Info

• Gene Symbol: COLEC12
• Gene Full Name: Collectin sub-family member 12
• Alias Symbols: CLP1, NSR2, SRCL, SCARA4
• NCBI Gene Id: 81035
• Protein Name: Collectin-12
• Description of Target: COLEC12 is a member of the C-lectin family,¡¡proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
• Uniprot ID: Q5KU26
• Protein Accession #: NP_569057
• Nucleotide Accession #: NM_130386
• Protein Size (# AA): 742
• Molecular Weight: 81kDa
• Protein Interactions: APP; EXOC1;