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Catalog No: ARP45877_P050
Price: $0.00
SKU
ARP45877_P050
Availability: Domestic: within 24 hours delivery | International: 3-5 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-COL18A1 (ARP45877_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Cow, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen for Anti-COL18A1 antibody is: synthetic peptide directed towards the Middle region of Human COIA1
PurificationAffinity purified
Predicted Homology Based on Immunogen SequenceCow: 92%; Horse: 83%; Human: 100%; Pig: 83%; Rabbit: 100%
Peptide SequenceSynthetic peptide located within the following region: VQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADD
Concentration0.5 mg/ml
Blocking PeptideFor Anti-COL18A1 antibody is Catalog # AAP45877
ReferenceN/A
Gene SymbolCOL18A1
Gene Full Namecollagen, type XVIII, alpha 1
Alias SymbolsKS, KNO, GLCC, KNO1
NCBI Gene Id80781
Protein NameCollagen alpha-1(XVIII) chain
Description of TargetThis gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.
Uniprot IDP39060-2
Protein Size (# AA)1339
Molecular Weight147 kDa
Protein InteractionsFUS; TUBG1; FBXO6; HNRNPD; TECPR1; GPC1; GPC4; KDR; FBLN2; ITGA5; MMP2; CTSL;
  1. What is the species homology for "COL18A1 Antibody - Middle region (ARP45877_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Cow, Horse, Pig, Rabbit".

  2. How long will it take to receive "COL18A1 Antibody - Middle region (ARP45877_P050)"?

    This item is available "Domestic: within 24 hours delivery | International: 3-5 days".

  3. What buffer format is "COL18A1 Antibody - Middle region (ARP45877_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "COL18A1 Antibody - Middle region (ARP45877_P050)"?

    This target may also be called "KS, KNO, GLCC, KNO1" in publications.

  5. What is the shipping cost for "COL18A1 Antibody - Middle region (ARP45877_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "COL18A1 Antibody - Middle region (ARP45877_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "COL18A1 Antibody - Middle region (ARP45877_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "147 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "COL18A1 Antibody - Middle region (ARP45877_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "COL18A1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "COL18A1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "COL18A1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "COL18A1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "COL18A1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "COL18A1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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