CNOT7 Antibody - N-terminal region (OASG01691)

Catalog No: OASG01691

Size:100 uL

Western Blot using HeLa

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human CNOT7. Location: 10-90aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: CNOT7 Polyclonal Antibody detects endogenous levels of CNOT7 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: CNOT7
• Gene Full Name: CCR4-NOT transcription complex, subunit 7
• Alias Symbols: CAF1, CAF-1, Caf1a, hCAF-1
• NCBI Gene Id: 29883; 18983;
• Description of Target: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
• Uniprot ID: Q9UIV1, Q60809
• Molecular Weight: 36 kDa