CNN1 Antibody (OAAD00126)

Catalog No: OAAD00126

Size:100 ug

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Chicken
• Clonality: Monoclonal
• Clone: CP-19
• Isotype: IgG1
• Host: Mouse
• Application: WB, IHC, IP, ICC
• Reconstitution and Storage: At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
• Immunogen: Turkey gizzard calponin
• Purification: Purified by the goat anti-mouse IgG Affinity chromatography.
• Specificity: Human, mouse, rat, chicken.
  No cross reactivity with other proteins.
• Formulation: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative.
• Application Info: Western blot At 0.25-0.5ug/ml with the appropriate system to detect calponin in cells and tissues.
  Immunohistochemistry(P) At 0.5-1ug/ml to detect calponin in formalin fixed and paraffin embedded tissues.
  Immunocytochemistry Suitable Other applications have not been tested.
  Optimal dilutions should be determined by end user.
• Storage Buffer: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
• Reference: Strasser, P.; Gimona, M.; Moessler, H.; Herzog, M.; Small, J. V. : Mammalian calponin: identification and expression of genetic variants. FEBS Lett. 330: 13-18, 1993.

Target Info

• Gene Symbol: CNN1
• Gene Full Name: Calponin-1
• Alias Symbols: SMCC, Sm-Calp, HEL-S-14
• NCBI Gene Id: 1264
• Protein Name: Calponin-1
• Description of Target: Calponin is a basic 34-kD protein first isolated from chicken gizzard and bovine aorta. It is specifically expressed in smooth muscle and binds calmodulin, actin, and tropomyosin. It is able to inhibit the ATPase activity of myosin and is thought to play a role in smooth muscle contraction. Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in some way in the regulation or modulation of contraction.
• Uniprot ID: P51911
• Protein Accession #: NP_001290.2
• Nucleotide Accession #: NM_001299.5