CLYBL Antibody - N-terminal region (ARP93729_P050)

Catalog No: ARP93729_P050

Host: Rabbit
Target Name: CLYBL
Sample Tissue: Rat Heart lysates
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Rat
• Predicted Species Reactivity: Rat
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of rat CLYBL
• Purification: Affinity purified
• Peptide Sequence: Synthetic peptide located within the following region: PRRAVLYVPGNDEKKIRKIPSLKVDCAVLDCEDGVAENKKNEARLRIAKT
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CLYBL (ARP93729_P050) antibody is Catalog # AAP93729

Target Info

• Gene Symbol: CLYBL
• Gene Full Name: citrate lyase beta like
• Alias Symbols: Cl, Clb, AI256068, 0610033J05Rik, 2310014M14Rik
• NCBI Gene Id: 69634
• Protein Name: citrate lyase subunit beta-like protein, mitochondrial
• Description of Target: Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway. The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite. Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate. Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. Also has very weak citramalate synthase activity in vitro.
• Uniprot ID: Q5I0K3
• Protein Accession #: NP_083832.2
• Nucleotide Accession #: NM_029556.3
• Protein Size (# AA): 338
• Molecular Weight: 37 kDa