Size:100 ul
$319.00
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SKU
ARP30645_P050
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Conjugation Options

ARP30645_P050-FITC Conjugated

ARP30645_P050-HRP Conjugated

ARP30645_P050-Biotin Conjugated

CLK4 Antibody - N-terminal region (ARP30645_P050)

Catalog#: ARP30645_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species ReactivityHuman
Predicted Species ReactivityCow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement ItemThis antibody may replace item sc-105214 from Santa Cruz Biotechnology.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CLK4
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 91%
Complete computational species homology dataAnti-CLK4 (ARP30645_P050)
Peptide SequenceSynthetic peptide located within the following region: RSRRSSPKRKRNRHCSSHQSRSKSHRRKRSRSIEDDEEGHLICQSGDVLR
ConcentrationBatch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking PeptideFor anti-CLK4 (ARP30645_P050) antibody is Catalog # AAP30645 (Previous Catalog # AAPP01302)
Datasheets/ManualsPrintable datasheet for anti-CLK4 (ARP30645_P050) antibody
Publications

Eisenreich, A. et al. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30, 462-70 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast 23604472

Gene SymbolCLK4
Official Gene Full NameCDC-like kinase 4
Alias SymbolsDKFZp686A20267
NCBI Gene Id57396
Protein NameDual specificity protein kinase CLK4
Description of TargetThe protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
Swissprot IdQ9HAZ1
Protein Accession #NP_065717
Nucleotide Accession #NM_020666
Protein Size (# AA)481
Molecular Weight57
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express CLK4.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express CLK4.
Protein InteractionsKPNA1; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; CLK4; SRRM2; AHCYL2; SUB1; RASA4; SRPK1; RNF181; CLASRP; UBL5; HSPB2;
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