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Catalog No: ARP52021_P050-Biotin
Size:100ul
Price: $434.00
SKU
ARP52021_P050-Biotin
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)

Datasheets/ManualsPrintable datasheet for anti-CLK1 (ARP52021_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CLK1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 85%
Peptide SequenceSynthetic peptide located within the following region: HSSAQENKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDYTQGC
Concentration0.5 mg/ml
Blocking PeptideFor anti-CLK1 (ARP52021_P050-Biotin) antibody is Catalog # AAP52021 (Previous Catalog # AAPP44291)
Sample Type Confirmation

CLK1 is supported by BioGPS gene expression data to be expressed in HEK293T

Publications

Eisenreich, A. et al. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30, 462-70 (2013). WB, Pig, Human, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Rat 23604472

Gene SymbolCLK1
Gene Full NameCDC-like kinase 1
Alias SymbolsCLK, STY, CLK/STY
NCBI Gene Id1195
Protein NameDual specificity protein kinase CLK1
Description of TargetThis gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.
Uniprot IDP49759
Protein Accession #NP_004062
Nucleotide Accession #NM_004071
Protein Size (# AA)484
Molecular Weight57kDa
Protein InteractionsKRTAP10-7; PDE9A; PRMT5; SRPK2; SRPK1; CLK1; BAG3; PIAS4; ISG15; UBC; YWHAG; LUC7L3; PPIG; SRSF6; PRPF4; GOLM1; UBL5; SRSF1; PTPN1; MBP; BCLAF1; NCOR1; SRSF3; SAFB;
  1. What is the species homology for "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)"?

    This target may also be called "CLK, STY, CLK/STY" in publications.

  5. What is the shipping cost for "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "57kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CLK1 Antibody - N-terminal region : Biotin (ARP52021_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CLK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CLK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CLK1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CLK1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CLK1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CLK1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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