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| Datasheets/Manuals | Printable datasheet for CLIC5 Antibody (OAEE00352) (OAEE00352) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Clonality | Monoclonal |
| Clone | CLIC5-02 |
| Isotype | IgG2b |
| Host | Mouse |
| Application | Flow cytometry|Western blot |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | KLH-conjugated peptide corresponding to the amino acids 160-173 of human CLIC5a (Cys-Ile-Asp-Ala-Asn-Thr-Ser-Asp-Lys-Gly-Ser-Arg-Arg coupled with KLH). |
| Purification | Purified |
| Concentration | 1 mg/ml |
| Specificity | Mouse monoclonal antibody CLIC5-02 recognizes CLIC5a, a 32 kDa protein which is component of actin complexes. Crossreactivity with CLIC5b was not determined. |
| Formulation | Purified |
| Purity | > 95% (by SDS-PAGE) |
| Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Reference | Wegner B, Al-Momany A, Kulak SC, Kozlowski K, Obeidat M, Jahroudi N, Paes J, Berryman M, Ballermann BJ: CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity. Am J Physiol Renal Physiol. 2010 Jun;298(6):F1492-503. |
| Gene Symbol | CLIC5 |
|---|---|
| Gene Full Name | chloride intracellular channel 5 |
| Alias Symbols | chloride intracellular channel protein 5;DFNB102;DFNB103;MST130;MSTP130. |
| NCBI Gene Id | 53405 |
| Protein Name | Chloride intracellular channel protein 5 |
| Description of Target | Required for normal hearing (PubMed:24781754). It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed:15184393, PubMed:18028448, PubMed:20335315). |
| Uniprot ID | Q9NZA1 |
| Protein Accession # | NP_001107558.1; NP_001242952.1; NP_058625.2 |
| Nucleotide Accession # | NM_001114086.1; NM_001256023.1; NM_016929.4 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CLIC5 Antibody (OAEE00352)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "CLIC5 Antibody (OAEE00352)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "CLIC5 Antibody (OAEE00352)" provided in?
This item is provided in "Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CLIC5 Antibody (OAEE00352)"?
This target may also be called "chloride intracellular channel protein 5;DFNB102;DFNB103;MST130;MSTP130." in publications.
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What is the shipping cost for "CLIC5 Antibody (OAEE00352)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CLIC5 Antibody (OAEE00352)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CLIC5 Antibody (OAEE00352)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CLIC5 Antibody (OAEE00352)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CLIC5"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CLIC5"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CLIC5"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CLIC5"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CLIC5"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CLIC5"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
