CLIC1 Protein (OPPA02273)

Catalog No: OPPA02273 (Formerly GWB-BSP431)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: CLIC1 Human solution containing 20mM Trsi HCL pH-8, 0.1M NaCl & 10% glycerol. Physical appearance: Sterile filtered colorless solution.
• Host: E. Coli
  Product Introduction: Chloride channels are various group of proteins that control fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, regulation of intracellular pH, and maintenance of cell volume. CLIC1 is part of the p64 family and is localized to the cell nucleus. CLIC1 displays both nuclear and plasma membrane chloride ion channel activity. CLIC1 inserts into membranes and forms chloride ion channels. CLIC1 channel activity depends on the pH. CLIC1 membrane insertion is redox-regulated and happens under oxydizing conditions.
  Product Description: CLIC1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 261amino acids (1-241a.a.) and having a molecular mass of 29 kDa. CLIC1 protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.
• Reconstitution and Storage: CLIC1 Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: GSSHHHHHH SSGLVPRGSH MAEEQPQVEL FVKAGSDGAK IGNCPFSQRL FMVLWLKGVT FNVTTVDTKR RTETVQKLCP GGQLPFLLYG TEVHTDTNKI EEFLEAVLCP PRYPKLAALN PESNTAGLDI FAKFSAYIKN SNPALNDNLE KGLLKALKVL DNYLTSPLPE EVDETSAEDE GVSQRKFLDG NELTLADCNL LPKLHIVQVV CKKYRGFTIP EAFRGVHRYL SNAYAREEFA STCPDDEEIE LAYEQVAKAL K.

Target Info

• Gene Symbol: CLIC1
• Alias Symbols: G6, CL1C1, NCC27, CLCNL1
• NCBI Gene Id: 1192
• Protein Name: Chloride intracellular channel protein 1
• Description of Target: Recombinant Human Chloride Intracellular Channel 1
• Uniprot ID: O00299
• Protein Accession #: NP_001279.2
• Protein Size (# AA): Recombinant