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CLCN6 Antibody - C-terminal region (ARP35334_T100)

100 ul
$229.00
In Stock
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Conjugation Options

ARP35334_T100-FITC Conjugated

ARP35334_T100-HRP Conjugated

ARP35334_T100-Biotin Conjugated

Gene Symbol:
CLCN6
Official Gene Full Name:
Chloride channel, voltage-sensitive 6
NCBI Gene Id:
1185
Protein Name:
Chloride transport protein 6
Swissprot Id:
Q5SNX3
Protein Accession #:
NP_068504
Nucleotide Accession #:
NM_021736
Alias Symbols:
CLC-6
Replacement Item:
This antibody may replace item sc-16439 from Santa Cruz Biotechnology.
Description of Target:
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.
Protein Size (# AA):
353
Molecular Weight:
39kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CLCN6.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CLCN6.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human CLCN6
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-CLCN6 (ARP35334_T100)
Peptide Sequence:
Synthetic peptide located within the following region: PQFQSISLRKIQFNFPYFRSDRDKRDFVSAGAAAGVAAAFGAPIGGTLFS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; PPP2R1A;
Blocking Peptide:
For anti-CLCN6 (ARP35334_T100) antibody is Catalog # AAP35334 (Previous Catalog # AAPP07254)
Datasheets/Manuals:
Printable datasheet for anti-CLCN6 (ARP35334_T100) antibody
Target Reference:
Tran,P., et al., (2002) Mamm. Genome 13 (9), 483-492
Publications:

Jensen, V. K. et al. A quantitative assay for lysosomal acidification rates in human osteoclasts. Assay Drug Dev. Technol. 9, 157-64 (2011). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 21050068

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