Size:100 ul
$249.00
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ARP35504_T100-HRP
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Conjugation Options

ARP35504_T100 Unconjugated

ARP35504_T100-FITC Conjugated

ARP35504_T100-Biotin Conjugated

CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)

Catalog#: ARP35504_T100-HRP
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Product Format Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Clonality Polyclonal
Host Rabbit
Conjugation HRP
Application IHC, WB
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Replacement Item This antibody may replace item sc-133466 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the C-terminal region of human CLCN3
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 91%; Zebrafish: 100%
Complete computational species homology data Anti-CLCN3 (ARP35504_T100)
Peptide Sequence Synthetic peptide located within the following region: VGDAFGREGIYEAHIRLNGYPFLDAKEEFTHTTLAADVMRPRRNDPPLAVL
Concentration 0.5 mg/ml
Blocking Peptide For anti-CLCN3 (ARP35504_T100-HRP) antibody is Catalog # AAP35504 (Previous Catalog # AAPP06744)
Datasheets/Manuals Printable datasheet for anti-CLCN3 (ARP35504_T100-HRP) antibody
Target Reference Salazar,G., et al., (2004) J. Biol. Chem. 279 (24), 25430-25439
Publications

Jensen, V. K. et al. A quantitative assay for lysosomal acidification rates in human osteoclasts. Assay Drug Dev. Technol. 9, 157-64 (2011). WB, Zebrafish, Human, Dog, Mouse, Bovine, Pig, Horse, Rabbit, Guinea pig, Rat, Sheep 21050068

Gene Symbol CLCN3
Official Gene Full Name Chloride channel, voltage-sensitive 3
Alias Symbols CLC3, ClC-3
NCBI Gene Id 1182
Protein Name H(+)/Cl(-) exchange transporter 3
Description of Target CLCN3 plays an important role in the cell proliferation of vascular smooth muscle cells. The PDZ-binding isoform of CLCN3 resides in the Golgi where it co-localizes with a small amount of CFTR (cystic fibrosis transmembrane conductance regulator).
Swissprot Id P51790
Protein Accession # NP_776297
Nucleotide Accession # NM_173872
Protein Size (# AA) 866
Molecular Weight 95kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CLCN3.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CLCN3.
Protein Interactions GOPC; SLC9A3R1; PDZK1; CLCN3; CFTR;
  1. What is the species homology for "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish".

  2. How long will it take to receive "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)"?

    This target may also be called "CLC3, ClC-3" in publications.

  5. What is the shipping cost for "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "95kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CLCN3 Antibody - C-terminal region : HRP (ARP35504_T100-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CLCN3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CLCN3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CLCN3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CLCN3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CLCN3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CLCN3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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