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CKAP4 antibody - middle region (ARP46790_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP46790_P050-FITC Conjugated

ARP46790_P050-HRP Conjugated

ARP46790_P050-Biotin Conjugated

Gene Symbol:
CKAP4
NCBI Gene Id:
10970
Official Gene Full Name:
Cytoskeleton-associated protein 4
Protein Name:
Cytoskeleton-associated protein 4
Swissprot Id:
Q07065
Protein Accession #:
NP_006816
Nucleotide Accession #:
NM_006825
Alias Symbols:
CLIMP-63, ERGIC-63, MGC99554, p63
Replacement Item:
This antibody may replace item sc-167469 from Santa Cruz Biotechnology.
Description of Target:
CKAP4/p63 is a substrate of DHHC2, a putative tumor suppressor. CK MNF116 and p63 were useful in identifying squamous cell carcinomas with single cell infiltration. Those results suggested a role of CKAP4/p63 in tumor.
Protein Size (# AA):
602
Molecular Weight:
66kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CKAP4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CKAP4.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human CKAP4
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%
Complete computational species homology data:
Anti-CKAP4 (ARP46790_P050)
Peptide Sequence:
Synthetic peptide located within the following region: SDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTEVQKRSQKE
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
FUS; UBC; TP53; SPRTN; SUMO1; NEDD8; MDM2; PARK2; ADRA1D; THOC7; HAMP; env; CCDC53; CKAP4; MVP; TSNAX; NKX3-1; NDUFB7; MYC; MLH1; ATF4; ECT2; COPS5; CUL3; SH3KBP1; ARRB1; ELAVL1; HDGF; CLN3; USP50; ASCC2; PLAT;
Blocking Peptide:
For anti-CKAP4 (ARP46790_P050) antibody is Catalog # AAP46790 (Previous Catalog # AAPP27588)
Datasheets/Manuals:
Printable datasheet for anti-CKAP4 (ARP46790_P050) antibody
Sample Type Confirmation:

CKAP4 is supported by BioGPS gene expression data to be expressed in HeLa

Additional Information:
IHC Information: Paraffin embedded breast tissue, tested with an antibody dilution of 5 ug/ml.
Target Reference:
Ko,C.J., (2008) J. Cutan. Pathol. 35 (4), 353-357
Publications:

Clark, R. et al. Comparative genomic and proteomic analysis of cytoskeletal changes in dexamethasone-treated trabecular meshwork cells. Mol. Cell. Proteomics 12, 194-206 (2013). IHC, WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 23105009

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