CITED2 Protein (OPPA02234)

Catalog No: OPPA02234 (Formerly GWB-4200D6)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The CITED2 solution contains 20mM Tris pH-8, 1mM DTT,0.1M NaCl & 50% glycerol. Physical appearance: Sterile Filtered colorless solution.
• Host: E. Coli
  Product Introduction: CITED2 is a significant transcriptional cofactor that takes part in multiple organ development. CITED2 is a cAMP-responsive element-binding protein (CBP)/p300 interacting transcriptional modulator and a negative regulator for HIF1A through its competitive binding with HIF1A to CBP/p300. CITED2 is essential for mouse fetal liver hematopoiesis and is necessary for the appropriate formation of the hyaloid vasculature and for lens morphogenesis. CITED2 is a coactivator of HNF4alpha and necessary for liver development. CITED2 is a coactivator of PPAR-alpha and both participate in signaling cascades of hypoxic response and angiogenesis.
  Product Description: CITED2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 278 amino acids (1-270 a.a.) and having a molecular mass of 29.5 kDa.The CITED2 is fused to 8 amino acid His Tag at C-terminus and purified by proprietary chromatographic techniques.
• Reconstitution and Storage: CITED2 although stable 4C for 4 weeks, should be stored desiccated below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Peptide Sequence: MADHMMAMNH GRFPDGTNGL HHHPAHRMGM GQFPSPHHHQ QQQPQHAFNA LMGEHIHYGA GNMNATSGIR HAMGPGTVNG GHPPSALAPA ARFNNSQFMGPPVASQGGSL PASMQLQKLN NQYFNHHPYP HNHYMPDLHP AAGHQMNGTN QHFRDCNPKH SGGSSTPGGS GGSSTPGGSG SSSGGGAGSS NSGGGSGSGN MPASVAHVPA AMLPPNVIDT DFIDEEVLMS LVIEMGLDRI KELPELWLGQ NEFDFMTDFV CKQQPSRVSC LEHHHHHH.

Target Info

• Gene Symbol: CITED2
• Alias Symbols: ASD8, MRG1, VSD2, MRG-1, P35SRJ
• NCBI Gene Id: 10370
• Protein Name: Cbp/p300-interacting transactivator 2
• Description of Target: Recombinant Human Cbp/p300-Interacting Transactivator 2
• Uniprot ID: Q99967
• Protein Accession #: NP_001161860.1
• Protein Size (# AA): Recombinant