CIRBP Recombinant Protein (OPCD02226)

Catalog No: OPCD02226

CIRBP Recombinant Protein (OPCD02226) using SDS-PAGE

CIRBP Recombinant Protein (OPCD02226) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-Glu172
  Subcellular Location: Nucleus, nucleoplasm. Cytoplasm
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CIRBP
• Gene Full Name: cold inducible RNA binding protein
• Alias Symbols: A18 hnRNP;CIRP;cold-inducible RNA-binding protein;glycine-rich RNA binding protein;Glycine-rich RNA-binding protein CIRP;testicular tissue protein Li 39.
• NCBI Gene Id: 1153
• Protein Name: Cold-inducible RNA-binding protein
• Description of Target: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
• Uniprot ID: Q14011
• Protein Accession #: NP_001271.1
• Nucleotide Accession #: NM_001280.2
• Protein Size (# AA): Met1~Glu172
• Molecular Weight: 22/27kDa