CIRBP Antibody - C-terminal region (OAAB05728)

Catalog No: OAAB05728

Size:400UL

Western blot analysis of CIRBP Antibody (C-term) in Y79 cell lysates (35ug/lane). CIRBP (arrow) was detected using the purified Pab.

Western blot analysis of CIRBP (arrow) using rabbit polyclonal CIRBP Antibody (C-term) either nontransfected (Lane 1) or lysates transiently transfected transfected (Lane 2) with the CIRBP gene.

CIRBP Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CIRBP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Hamster|Human|Mouse|Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: IHC-P,WB
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This CIRBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: CIRBP
• Alias Symbols: A18 hnRNP, C, CIRP, cold-inducible RNA-binding protein, glycine-rich RNA binding protein, glycine-rich RNA-binding protein CIRP, I79_009223, R74941, testicular tissue protein Li 39.
• NCBI Gene Id: 100689075|1153|12696|81825
• Protein Name: Cold-inducible RNA-binding protein|cold-inducible RNA-binding protein isoform 1 [Homo sapiens]
• Description of Target: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.|Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed (By similarity).|Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.
• Uniprot ID: P60824|P60825|P60826|Q14011
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001271.1
• Molecular Weight: 18648