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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for CILP Antibody (OACD02536) |
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Predicted Species Reactivity | Mouse |
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Product Format | Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
Reconstitution and Storage | 2°C to 8°C|-20°C |
Immunogen | Recombinant CILP (Pro604~His864) expressed in E.coli |
Purification | Affinity Purified; Protein A Purified |
Concentration | 0.45 mg/ml |
Specificity | The antibody is a rabbit polyclonal antibody raised against CILP. It has been selected for its ability to recognize CILP in immunohistochemical staining and western blotting. |
Application Info | WB: 0.5-2 ug/mL IHC: 5-20 ug/mL ICC: 5-20 ug/mL |
Gene Symbol | Cilp |
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Gene Full Name | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
Alias Symbols | 9830114D16;C130036G17Rik;cartilage intermediate layer protein 1;CILP-1. |
NCBI Gene Id | 214425 |
Protein Name | Cartilage intermediate layer protein 1 |
Description of Target | Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity). |
Uniprot ID | Q66K08 |
Protein Accession # | NP_775561.1 |
Nucleotide Accession # | NM_173385 |
Molecular Weight | 132 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CILP Antibody (OACD02536)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".
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How long will it take to receive "CILP Antibody (OACD02536)"?
This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".
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What buffer format is "CILP Antibody (OACD02536)" provided in?
This item is provided in "Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CILP Antibody (OACD02536)"?
This target may also be called "9830114D16;C130036G17Rik;cartilage intermediate layer protein 1;CILP-1." in publications.
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What is the shipping cost for "CILP Antibody (OACD02536)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CILP Antibody (OACD02536)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CILP Antibody (OACD02536)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "132 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CILP Antibody (OACD02536)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "Cilp"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "Cilp"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "Cilp"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "Cilp"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "Cilp"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "Cilp"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.