CHP Protein (OPPA02266)

Catalog No: OPPA02266 (Formerly GWB-BSP429)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: CHP Human solution containing 20mM Tris HCL pH-7.5, & 10% glycerol. Physical appearance: Sterile filtered colorless solution.
• Host: E. Coli
  Product Introduction: Calcium-binding protein P22 is a phosphoprotein that binds to the sodium-hydrogen exchangers (NHEs). CHP is an essential cofactor which maintains the physiological activity of NHE family members. CHP has protein sequence resemblance to calcineurin B and it is also identified to be an endogenous inhibitor of calcineurin activity.CHP is necessary for constitutive membrane traffic. CHP Inhibits GTPase-stimulated Na(+)/H(+) exchange. CHP inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1.
  Product Description: CHP Recombinant E.coli produced in E.Coli is a single, non-glycosylated polypeptide chain containing 216 amino acids (1-195 a.a.) and having a molecular mass of 24.7 kDa. The CHP is fused to 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
• Reconstitution and Storage: CHP Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MMGSRASTLL RDEELEEIKK ETGFSHSQIT RLYSRFTSLD KGENGTLSRE DFQRIPELAI NPLGDRIINA FFPEGEDQVN FRGFMRTLAH FRPIEDNEKS KDVNGPEPLN SRSNKLHFAF RLYDLDKDEK ISRDELLQVL RMMVGVNISD EQLGSIADRT IQEADQDGDS AISFTEFVKV LEKVDVEQKM SIRFLH.

Target Info

• Gene Symbol: CHP
• Alias Symbols: CHP, p22, p24, SPAX9, Sid470p, SLC9A1BP
• NCBI Gene Id: 11261
• Protein Name: Calcineurin B homologous protein 1
• Description of Target: Recombinant Human Calcium Binding Protein P22
• Uniprot ID: Q99653
• Protein Accession #: NP_009167.1
• Protein Size (# AA): Recombinant