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Datasheets/Manuals | Printable datasheet for CHMP2A Antibody - FITC Conjugated (OACA01169) (OACA01169) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | FITC |
Application | WB |
Reconstitution and Storage | -20°C or -80°C |
Immunogen | Recombinant Human Charged multivesicular body protein 2a protein (1-222AA) |
Purification | Protein G Purified |
Purity | Caprylic Acid Ammonium Sulfate Precipitation purified |
Reference | [1] NovelFam3000 -- uncharacterized human protein domains conserved across model organisms.'Kemmer D., Podowski R.M., Arenillas D., Lim J., Hodges E., Roth P., Sonnhammer E.L.L., Hoeoeg C., Wasserman W.W.BMC Genomics 7:48-48(2006) [2] Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.'Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.Nat. Biotechnol. 21:566-569(2003) [3] CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.'Howard T.L., Stauffer D.R., Degnin C.R., Hollenberg S.M.J. Cell Sci. 114:2395-2404(2001) |
Storage Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Gene Symbol | CHMP2A |
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Gene Full Name | charged multivesicular body protein 2A |
Alias Symbols | BC2;BC-2;charged multivesicular body protein 2a;CHMP2;chromatin modifying protein 2A;Chromatin-modifying protein 2a;putative breast adenocarcinoma marker (32kD);putative breast adenocarcinoma marker BC-2;vacuolar protein sorting-associated protein 2-1;VPS2;VPS2 homolog A;vps2-1;VPS2A. |
NCBI Gene Id | 27243 |
Protein Name | Charged multivesicular body protein 2a |
Description of Target | Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. |
Uniprot ID | O43633 |
Protein Accession # | NP_055268.1; NP_940818.1 |
Nucleotide Accession # | NM_014453.3; NM_198426.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CHMP2A Antibody - FITC Conjugated (OACA01169)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "CHMP2A Antibody - FITC Conjugated (OACA01169)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "CHMP2A Antibody - FITC Conjugated (OACA01169)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CHMP2A Antibody - FITC Conjugated (OACA01169)"?
This target may also be called "BC2;BC-2;charged multivesicular body protein 2a;CHMP2;chromatin modifying protein 2A;Chromatin-modifying protein 2a;putative breast adenocarcinoma marker (32kD);putative breast adenocarcinoma marker BC-2;vacuolar protein sorting-associated protein 2-1;VPS2;VPS2 homolog A;vps2-1;VPS2A." in publications.
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What is the shipping cost for "CHMP2A Antibody - FITC Conjugated (OACA01169)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CHMP2A Antibody - FITC Conjugated (OACA01169)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CHMP2A Antibody - FITC Conjugated (OACA01169)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CHMP2A Antibody - FITC Conjugated (OACA01169)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CHMP2A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CHMP2A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CHMP2A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CHMP2A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CHMP2A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CHMP2A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.