Catalog No: AVARP13011_P050
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AVARP13011_P050
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Datasheets/ManualsPrintable datasheet for anti-CHM (AVARP13011_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Horse
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CHM
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceHorse: 80%; Human: 100%
Peptide SequenceSynthetic peptide located within the following region: LHVDSRSYYGGNWASFSFSGLLSWLKEYQENSDIVSDSPVWQDQILENEE
Concentration0.5 mg/ml
Blocking PeptideFor anti-CHM (AVARP13011_P050) antibody is Catalog # AAP30666 (Previous Catalog # AAPP01323)
ReferenceFujita,Y., (2008) Invest. Ophthalmol. Vis. Sci. 49 (4), 1315-1321
Gene SymbolCHM
Gene Full NameChoroideremia (Rab escort protein 1)
Alias SymbolsTCD, GGTA, REP-1, DXS540, HSD-32
NCBI Gene Id1121
Protein NameRab proteins geranylgeranyltransferase component A 1
Description of TargetCHM binds unprenylated Rab proteins, presents it to the catalytic Rab GGTase dimer, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.The choroideremia gene encodes for a protein, the Rab escort protein-1 (REP1), which is involved in membrane trafficking.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP24386
Protein Accession #NP_000381
Nucleotide Accession #NM_000390
Protein Size (# AA)653
Molecular Weight73kDa
Protein InteractionsUBC; RAB1B; RAB32; RAB14; RAB3D; RAB7A; RAB18; RAB5B; RAB6A; RAB4A; RAB3B; RAB3A; RAB5A; RAB1A;
  1. What is the species homology for "CHM Antibody - N-terminal region (AVARP13011_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Horse".

  2. How long will it take to receive "CHM Antibody - N-terminal region (AVARP13011_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CHM Antibody - N-terminal region (AVARP13011_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CHM Antibody - N-terminal region (AVARP13011_P050)"?

    This target may also be called "TCD, GGTA, REP-1, DXS540, HSD-32" in publications.

  5. What is the shipping cost for "CHM Antibody - N-terminal region (AVARP13011_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CHM Antibody - N-terminal region (AVARP13011_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CHM Antibody - N-terminal region (AVARP13011_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "73kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CHM Antibody - N-terminal region (AVARP13011_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CHM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CHM"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CHM"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CHM"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CHM"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CHM"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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