CHIT1 Antibody (OAGA00108)

Catalog No: OAGA00108

Size:100 ul

Sample (30 ug of whole cell lysate)
A: Hela
10% SDS PAGE
OAGA00108 diluted at 1:1000

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Additional Information: Background: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq]
  Positive Controls: A549, HeLa, Jurkat
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant fragment corresponding to a region within amino acids 216 and 463 of Chitotriosidase (Uniprot ID#Q13231)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: CHIT1
• Gene Full Name: Chitotriosidase-1
• Alias Symbols: CHI3, CHIT, CHITD
• NCBI Gene Id: 1118
• Protein Name: Chitotriosidase-1
• Uniprot ID: Q13231
• Protein Accession #: NP_003456.1
• Molecular Weight: 52 kDa