Catalog No: OPCD03632
Price: $0.00
SKU
OPCD03632
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Datasheets/Manuals | Printable datasheet for CHI3L1 Recombinant Protein (OPCD03632) |
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Predicted Species Reactivity | Rat|Rattus norvegicus |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Tyr117-Lys364 |
:: | Subcellular Location: Secreted, extracellular space. Cytoplasm, perinuclear region. Endoplasmic reticulum |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 95% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | Chi3l1 |
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Gene Full Name | chitinase 3 like 1 |
Alias Symbols | cartilage glycoprotein 39;CGP-39;Chil1;chitinase 3-like 1 (cartilage glycoprotein-39);chitinase 3-like 1 protein;chitinase-3-like protein 1;GP-39. |
NCBI Gene Id | 89824 |
Protein Name | Chitinase-3-like protein 1 |
Description of Target | Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity). |
Uniprot ID | Q9WTV1 |
Protein Accession # | NP_001296749.1 |
Nucleotide Accession # | NM_001309820.1 |
Protein Size (# AA) | Tyr117~Lys364 |
Molecular Weight | 29kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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