CHI3L1 Recombinant Protein (OPCD03630)

Catalog No: OPCD03630

CHI3L1 Recombinant Protein (OPCD03630) using SDS-PAGE

CHI3L1 Recombinant Protein (OPCD03630) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asn112-Lys377
  Subcellular Location: Secreted, extracellular space.
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: CHI3L1
• Gene Full Name: chitinase 3 like 1
• Alias Symbols: 39 kDa synovial protein;ASRT7;cartilage glycoprotein 39;CGP-39;chitinase 3-like 1 (cartilage glycoprotein-39);chitinase-3-like protein 1;GP39;GP-39;hCGP-39;HC-gp39;HCGP-3P;YK-40;YKL40;YKL-40;YYL-40.
• NCBI Gene Id: 1116
• Protein Name: Chitinase-3-like protein 1
• Description of Target: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
• Uniprot ID: P36222
• Protein Accession #: NP_001267.2
• Nucleotide Accession #: NM_001276.2
• Protein Size (# AA): Asn112~Thr237+Ile299~Lys377
• Molecular Weight: 26kDa