CHGA Antibody (OAAF08275)

Catalog No: OAAF08275

Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Small cell lung carcinoma using Chromogranin A antibody.

Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Small cell lung carcinoma using Chromogranin A antibody.

Product Info

• Tested Species Reactivity: Human
• Product Format: Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20
• Clonality: Monoclonal
• Clone: ABT-CGA
• Isotype: IgG
• Host: Mouse
• Application: IHC-P
• Additional Information: Retrieval buffer: TRIS-EDTA of pH8.0
  Description: Mouse monoclonal to Chromogranin A
• Reconstitution and Storage: Shipped at 4C. Store at -20C. Stable for 12 months at -20C.
• Immunogen: The antiserum was produced against synthesized peptide derived between 70-110 aa of human CHGA. The exact sequence is proprietary.
• Purification: Immunogen affinity purified
• Specificity: Anti-Chromogranin A [ABT-CGA] detects endogenous levels of total Chromogranin A protein.
• Application Info: IHC 1:200 - 1:400

Target Info

• Gene Symbol: CHGA
• Gene Full Name: chromogranin A
• Alias Symbols: CGA
• NCBI Gene Id: 1113
• Protein Name: chromogranin-A
• Description of Target: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: P10645
• Protein Accession #: NP_001266.1
• Nucleotide Accession #: XM_011536370.1
• Molecular Weight: 51  kDa