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Catalog No: ARP32459_P050
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ARP32459_P050
Availability: Domestic: within 24 hours delivery | International: 3-5 days
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CHD3 Antibody - C-terminal region (ARP32459_P050)

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Datasheets/ManualsPrintable datasheet for anti-CHD3 (ARP32459_P050) antibody
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human CHD3
PurificationAffinity purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: RKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKR
Concentration0.5 mg/ml
Blocking PeptideFor anti-CHD3 (ARP32459_P050) antibody is Catalog # AAP32459
Gene SymbolCHD3
Gene Full Namechromodomain helicase DNA binding protein 3
Alias SymbolsZFH, Mi-2a, SNIBCPS, Mi2-ALPHA
NCBI Gene Id1107
Protein NameChromodomain-helicase-DNA-binding protein 3
Description of TargetThis gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Uniprot IDQ12873
Protein Accession #NP_005843
Nucleotide Accession #NM_005852.4
Protein Size (# AA)2000
Molecular Weight220 kDa
Protein InteractionsTRIM28; SUMO2; UBC; LGR4; RNF2; BMI1; SOX2; HDAC2; HDAC1; SIRT1; SKIL; HDAC3; SMARCC2; RBBP7; RBBP4; CHD4; GATAD2A; MBD3; MTA2; IKZF1; GIT1; ZHX1; IMMT; TCERG1; VIM; TP53; TAL1; PTN; NEFL; KPNB1; PIAS4; LRIF1; PRPF40A; HTT; CHD3; BARD1; TWIST1; KDM1A; KDM
  1. What is the species homology for "CHD3 Antibody - C-terminal region (ARP32459_P050)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "CHD3 Antibody - C-terminal region (ARP32459_P050)"?

    This item is available "Domestic: within 24 hours delivery | International: 3-5 days".

  3. What buffer format is "CHD3 Antibody - C-terminal region (ARP32459_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CHD3 Antibody - C-terminal region (ARP32459_P050)"?

    This target may also be called "ZFH, Mi-2a, SNIBCPS, Mi2-ALPHA" in publications.

  5. What is the shipping cost for "CHD3 Antibody - C-terminal region (ARP32459_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CHD3 Antibody - C-terminal region (ARP32459_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CHD3 Antibody - C-terminal region (ARP32459_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "220 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CHD3 Antibody - C-terminal region (ARP32459_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CHD3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CHD3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CHD3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CHD3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CHD3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CHD3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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