Size:100 ul
$315.00
In Stock
SKU
OACA02431
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More Information
Predicted Species Reactivity Human
Product Format Liquid PBS with 0.02% sodium azide with 50% glycerol (pH 7.3)
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application IHC, CHIP, ELISA
Reconstitution and Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Replacement Item This antibody may replace item sc-134751 from Santa Cruz Biotechnology.
Immunogen Recombinant human Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710aa)
Purification Antigen Affinity Purified
Predicted Homology Based on Immunogen Sequence Human
Concentration Varies by lot. See vial for concentration.
Datasheets/Manuals Printable datasheet for anti-CDH1 (OACA02431) antibody
Application Info IHC: 1:20~200
Target Reference [1] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). The MGC Project TeamGenome Res. 14:2121-2127 (2004).
[2] Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. Sims R.J. III, Chen C.-F., Santos-Rosa H., Kouzarides T., Patel S.S., Reinberg D.J. Biol. Chem. 280:41789-41792 (2005).
Gene Symbol CHD1
Official Gene Full Name chromodomain helicase DNA binding protein 1
NCBI Gene Id 1105
Protein Name chromodomain-helicase-DNA-binding protein 1
Description of Target ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity. Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells.
Swissprot Id O14646
Protein Accession # NP_001261.2
Nucleotide Accession # NM_001270.2
Protein Size (# AA) 1710
Molecular Weight 197 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express CHD1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express CHD1.
  1. What is the species homology for "CHD1 Antibody (OACA02431)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "CHD1 Antibody (OACA02431)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "CHD1 Antibody (OACA02431)" provided in?

    This item is provided in "Liquid PBS with 0.02% sodium azide with 50% glycerol (pH 7.3)".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CHD1 Antibody (OACA02431)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "CHD1 Antibody (OACA02431)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CHD1 Antibody (OACA02431)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CHD1 Antibody (OACA02431)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "197 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CHD1 Antibody (OACA02431)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "CHD1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CHD1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CHD1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CHD1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CHD1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CHD1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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