CHCHD3 Antibody - N-terminal region : HRP (ARP57039_P050-HRP)

Catalog No: ARP57039_P050-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CHCHD3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Sheep: 86%
• Peptide Sequence: Synthetic peptide located within the following region: RMKESSPSGSKSQRYSGAYGASVSDEELKRRVAEELALEQAKKESEDQKR
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CHCHD3 (ARP57039_P050-HRP) antibody is Catalog # AAP57039 (Previous Catalog # AAPP40532)
• Reference: 0
• Publications:

  Ott, C. et al. Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes. Mol. Cell. Biol. 32, 1173-88 (2012). WB, Human, Mouse, Rat, Guinea pig, Sheep, Dog, Horse, Rabbit, Bovine 22252321

  Darshi, M., Trinh, K. N., Murphy, A. N. & Taylor, S. S. Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. J. Biol. Chem. 287, 39480-91 (2012). WB, Human, Mouse, Rat, Guinea pig, Sheep, Dog, Horse, Rabbit, Bovine 23019327

Target Info

• Gene Symbol: CHCHD3
• Gene Full Name: Coiled-coil-helix-coiled-coil-helix domain containing 3
• Alias Symbols: Mic19, MINOS3, MICOS19, PPP1R22
• NCBI Gene Id: 54927
• Protein Name: Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial
• Description of Target: The function of this protein remains unknown.
• Uniprot ID: Q9NX63
• Protein Accession #: NP_060282
• Nucleotide Accession #: NM_017812
• Protein Size (# AA): 227
• Molecular Weight: 26kDa
• Protein Interactions: NOTCH2NL; SPERT; KRT40; SSX2IP; RAB3IP; LZTS2; USHBP1; CCDC33; GMCL1P1; RPGRIP1; FANCL; SAMM50; SPAG5; CALCOCO2; PDE4DIP; BLZF1; TRAF1; TRIM27; GOLGA2; UBC; GPRASP2; MDM2; SUZ12; RNF2; EZH2; PARK2; HDAC8; NPM1; PAN2; PPP1CA; MYC; FMNL1; MDC1; ECT2; SNRPD3