Catalog No: OAGA01036
Size:100 ul
Price: $372.00
SKU
OAGA01036
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-CFL2 antibody - OAGA01036
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationICC, IF, WB
Additional InformationBackground: Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. (Gillett et al., 1996 [PubMed 8800436]). Cofilin-2 is a member of the AC group of proteins that also includes cofilin-1 (CFL1) and destrin (DSTN; MIM 609114), all of which regulate actin-filament dynamics (Bamburg et al., 1999 [PubMed 10461190]; Maciver and Hussey, 2002). The CFL2 gene encodes a skeletal muscle-specific isoform (Vartiainen et al., 2002 [PubMed 11809832]) localized to the thin filaments, where it exerts its effect on actin, in part through interactions with tropomyosins (Ono and Ono, 2002 [PubMed 11901171]).[supplied by OMIM]
::Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain
::Cellular Localization: Nucleus matrix, Cytoplasm, cytoskeleton
Reconstitution and StorageKeep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 166 of Cofilin 2 (muscle) (Uniprot ID#Q9Y281)
PurificationPurified by antigen-affinity chromatography.
Concentration0.24 mg/ml
Application InfoSuggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Gene SymbolCFL2
Gene Full NameCofilin-2
Alias SymbolsNEM7
NCBI Gene Id1073
Protein NameCofilin-2
Uniprot IDQ9Y281
Protein Accession #NP_068733.1
Molecular Weight19 kDa
  1. What is the species homology for "CFL2 Antibody (OAGA01036)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "CFL2 Antibody (OAGA01036)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "CFL2 Antibody (OAGA01036)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CFL2 Antibody (OAGA01036)"?

    This target may also be called "NEM7" in publications.

  5. What is the shipping cost for "CFL2 Antibody (OAGA01036)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CFL2 Antibody (OAGA01036)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CFL2 Antibody (OAGA01036)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "19 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CFL2 Antibody (OAGA01036)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CFL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CFL2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CFL2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CFL2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CFL2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CFL2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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