CEBPZ Antibody - N-terminal region (ARP38679_P050)

Catalog No: ARP38679_P050

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Host: Rabbit
Target Name: CEBPZ
Sample Tissue: Human OVCAR-3 Whole Cell lysates
Antibody Dilution: 1ug/ml

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPZ
• Purification: Affinity purified
• Predicted Homology Based on Immunogen Sequence: Cow: 77%; Horse: 80%; Human: 100%; Mouse: 80%; Pig: 77%; Rabbit: 85%; Rat: 82%; Yeast: 83%; Zebrafish: 83%
• Peptide Sequence: Synthetic peptide located within the following region: MAAVKEPLEFHAKRPWRPEEAVEDPDEEDEDNTSEAENGFSLEEVLRLGG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CEBPZ (ARP38679_P050) antibody is Catalog # AAP38679

Target Info

• Gene Symbol: CEBPZ
• Gene Full Name: CCAAT enhancer binding protein zeta
• Alias Symbols: CBF, CBF2, NOC1, HSP-CBF
• NCBI Gene Id: 10153
• Protein Name: CCAAT/enhancer-binding protein zeta
• Description of Target: This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML).
• Uniprot ID: Q03701
• Protein Accession #: NP_005751
• Nucleotide Accession #: NM_005760.3
• Protein Size (# AA): 1054
• Molecular Weight: 115 kDa
• Protein Interactions: UBC; TARBP2; EED; RNF2; HDAC11; SIRT7; SUMO2; RELA; RPS6KA6; LAMTOR3; PRKRA; UBE3A; HMOX2; GSK3B; ZBTB7B; LZTR1; STAT6; RXRG; PCBD1; TP73; TP53; NFYB; LAG3;