CEBPA Antibody - N-terminal region (P100908_P050)

Catalog No: P100908_P050

WB Suggested Anti-CEBPA Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysateCEBPA is supported by BioGPS gene expression data to be expressed in HepG2

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Pig
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Guinea Pig: 90%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: GGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CEBPA (P100908_P050) antibody is Catalog # AAP31256 (Previous Catalog # AAPP02005)
• Sample Type Confirmation:

  CEBPA is supported by BioGPS gene expression data to be expressed in HepG2

• Reference: Zhu,Q.S., et al., (2004) J. Biol. Chem. 279 (29), 29902-29910
• Description:
  View product citations for CEBPA Antibody - N-terminal region (P100908_P050)on CiteAb

Target Info

• Gene Symbol: CEBPA
• Gene Full Name: CCAAT/enhancer binding protein (C/EBP), alpha
• Alias Symbols: CEBP, C/EBP-alpha
• NCBI Gene Id: 1050
• Protein Name: CCAAT/enhancer-binding protein alpha
• Description of Target: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
• Uniprot ID: P49715
• Protein Accession #: NP_004355
• Nucleotide Accession #: NM_004364
• Protein Size (# AA): 358
• Molecular Weight: 38kDa
• Protein Interactions: CEBPB; ZBTB16; RARA; HDAC1; BHLHE41; UBC; CEBPE; BATF2; BATF3; YY1AP1; ATF5; BATF; FOSL1; FOS; DBP; CEBPG; CEBPA; ATF4; ATF3; UBE3A; SKP2; RASGRF1; C1QBP; CDKN1A; SRA1; CDK4; PIAS1; Fbxw7; GRIN3A; RAB34; NAA16; POLR1E; MRTO4; AK5; MACF1; KAT5; AKAP9; SMC1