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CDX2 antibody - middle region (ARP31476_P050)

100 ul
$289.00
In Stock

Conjugation Options

ARP31476_P050-FITC Conjugated

ARP31476_P050-HRP Conjugated

ARP31476_P050-Biotin Conjugated

Gene Symbol:
CDX2
NCBI Gene Id:
1045
Official Gene Full Name:
Caudal type homeobox 2
Protein Name:
Homeobox protein CDX-2
Swissprot Id:
Q99626
Protein Accession #:
NP_001256
Nucleotide Accession #:
NM_001265
Alias Symbols:
CDX3, CDX-3
Replacement Item:
This antibody may replace item sc-130716 from Santa Cruz Biotechnology.
Description of Target:
CDX2 encodes a protein that plays an important role in gallbladder carcinogenesis with intestinal differentiation. Cdx2 is a highly sensitive marker for Barrett's esophagus.
Protein Size (# AA):
313
Molecular Weight:
34kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CDX2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CDX2.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human CDX2
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 91%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-CDX2 (ARP31476_P050)
Peptide Sequence:
Synthetic peptide located within the following region: QRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRY
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
CDK2; SMARCD1; SMARCB1; SMARCA4; SMARCA2; KDM5B; UBB; PAX6; GSK3B; EP300; CDX2; MAPK14; CREBBP; MAPK1; HNF1A; ACAT2;
Blocking Peptide:
For anti-CDX2 (ARP31476_P050) antibody is Catalog # AAP31476 (Previous Catalog # AAPP02238)
Datasheets/Manuals:
Printable datasheet for anti-CDX2 (ARP31476_P050) antibody
Target Reference:
Saad,R.S., et al., (2004) J. Clin. Pathol. 122 (3), 421-427
Publications:

Tajbakhsh, J. Covisualization of methylcytosine, global DNA, and protein biomarkers for In Situ 3D DNA methylation phenotyping of stem cells. Methods Mol. Biol. 1052, 77-88 (2013). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 23593143

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