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CDKN2B Antibody - C-terminal region (OAAB10438)

Catalog#: OAAB10438
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species ReactivityHuman
Product FormatPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Additional InformationPrecautions: CDKN2B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
::Function: Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest
::Cellular Location: Cytoplasm. Note=Also found in the nucleus.
Tissue Location: Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement ItemThis antibody may replace item sc-1429 from Santa Cruz Biotechnology.
ImmunogenThis CDKN2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the C-terminal region of human CDKN2B.
Predicted Homology Based on Immunogen SequenceHuman
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/ManualsPrintable datasheet for OAAB10438
Application InfoFC: 1:25
WB: 1:2000
Gene SymbolCDKN2B
Alias SymbolsCDKN2B, MTS2, Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, p14-INK4b, p15-INK4b
NCBI Gene Id1030
Protein NameCyclin-dependent kinase 4 inhibitor B
Description of TargetPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Swissprot IdP42772
Protein Accession #NP_004927.2
Molecular Weight14722 Da
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express CDKN2B.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express CDKN2B.
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