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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAF08364 |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Product Format | Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20 |
| Clonality | Monoclonal |
| Clone | ABT-p27 |
| Isotype | IgG |
| Host | Mouse |
| Application | WB, IHC-P |
| Additional Information | Retrieval buffer: TRIS-EDTA of pH8.0 |
| :: | Description: Mouse monoclonal to p27Kip1 |
| Reconstitution and Storage | Shipped at 4C. Store at -20C. Stable for 12 months at -20C. |
| Immunogen | The antiserum was produced against synthesized peptide derived between 150-198 aa of human CDKN1B. The exact sequence is proprietary. |
| Purification | Immunogen affinity purified |
| Specificity | Anti-p27Kip1 [ABT-p27] detects endogenous levels of total p27Kip1 protein. |
| Application Info | IHC 1:200 - 1:400, WB 1:100 - 1:500 |
| Gene Symbol | CDKN1B |
|---|---|
| Gene Full Name | cyclin dependent kinase inhibitor 1B |
| Alias Symbols | KIP1, MEN4, CDKN4, MEN1B, P27KIP1 |
| NCBI Gene Id | 1027 |
| Protein Name | cyclin-dependent kinase inhibitor 1B |
| Description of Target | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). |
| Uniprot ID | P46527 |
| Protein Accession # | NP_004055.1 |
| Nucleotide Accession # | NM_004064.4 |
| Molecular Weight | 22 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CDKN1B Antibody (OAAF08364)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "".
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How long will it take to receive "CDKN1B Antibody (OAAF08364)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "CDKN1B Antibody (OAAF08364)" provided in?
This item is provided in "Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CDKN1B Antibody (OAAF08364)"?
This target may also be called "KIP1, MEN4, CDKN4, MEN1B, P27KIP1" in publications.
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What is the shipping cost for "CDKN1B Antibody (OAAF08364)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CDKN1B Antibody (OAAF08364)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CDKN1B Antibody (OAAF08364)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "22 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CDKN1B Antibody (OAAF08364)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CDKN1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CDKN1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CDKN1B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CDKN1B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CDKN1B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CDKN1B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
