Catalog No: OAAF02895
Size:100 ug
Price: $344.00
SKU
OAAF02895
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for CDK5RAP2 Antibody (OAAF02895)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin
Reconstitution and Storage-20°C
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDK5RAP2.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SpecificityCDK5RAP2 antibody detects endogenous levels of total CDK5RAP2 protein.
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
DilutionThe optimal working dilution should be determined by the end user.
Application InfoIHC: 1:50~1:100; ELISA: 1:20000
ReferenceNagase T., DNA Res. 7:273-281(2000).
Humphray S.J., Nature 429:369-374(2004).
Ota T., Nat. Genet. 36:40-45(2004).
Gene SymbolCDK5RAP2
Gene Full NameCDK5 regulatory subunit associated protein 2
Alias SymbolsC48;CDK5 activator-binding protein C48;CDK5 regulatory subunit-associated protein 2;centrosomal protein 215 kDa;Centrosome-associated protein 215;centrosomin;Cep215;MCPH3.
NCBI Gene Id55755
Protein NameCDK5 regulatory subunit-associated protein 2
Description of TargetPotential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with EB1/MAPRE1, may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of the gamma-tubulin ring complex (gamma-TuRC) onto centrosomes (PubMed:26485573). In complex with PDE4DIP isoform 13/MMG8/SMYLE, MAPRE1 and AKAP9, contributes to microtubules nucleation and extension from the centrosome to the cell periphery (PubMed:29162697). Required for the recruitment of AKAP9 to centrosomes (PubMed:29162697). Plays a role in neurogenesis (By similarity).
Uniprot IDQ96SN8
Protein Accession #NP_001011649.1
Molecular Weight215 kDa
  1. What is the species homology for "CDK5RAP2 Antibody (OAAF02895)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "CDK5RAP2 Antibody (OAAF02895)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "CDK5RAP2 Antibody (OAAF02895)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CDK5RAP2 Antibody (OAAF02895)"?

    This target may also be called "C48;CDK5 activator-binding protein C48;CDK5 regulatory subunit-associated protein 2;centrosomal protein 215 kDa;Centrosome-associated protein 215;centrosomin;Cep215;MCPH3." in publications.

  5. What is the shipping cost for "CDK5RAP2 Antibody (OAAF02895)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CDK5RAP2 Antibody (OAAF02895)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CDK5RAP2 Antibody (OAAF02895)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "215 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CDK5RAP2 Antibody (OAAF02895)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CDK5RAP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CDK5RAP2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CDK5RAP2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CDK5RAP2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CDK5RAP2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CDK5RAP2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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