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CDK1 Antibody (Phospho-Thr14) (OAAN02724)
| Datasheets/Manuals | Printable datasheet for anti-CDK1 (OAAN02724) |
|---|
| Predicted Species Reactivity | Human, Mouse, Rat |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | WB, IF |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Thr14 of human CDK1 |
| Purification | Affinity purified against immunogen |
| Preservative | 0.02% Sodium Azide |
| Target Post-Translational Modification | Phospho-Thr14 |
| Application Info | WB: 1:500 - 1:1,000. IF: 1:50 - 1:100 |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Publications | The 5.8S pre-rRNA maturation factor, M-phase phosphoprotein 6, is a female fertility factor required for oocyte quality and meiosis. Cell Prolif. 53, e12769 (2020). 32003502 The ubiquitin ligase KBTBD8 regulates PKM1 levels via Erk1/2 and Aurora A to ensure oocyte quality. Aging (Albany NY). 11, 1110-1128 (2019). 30786262 |
| Description |
| Gene Symbol | CDK1 |
|---|---|
| Gene Full Name | cyclin-dependent kinase 1 |
| Alias Symbols | CDC2, CDC28A, P34CDC2 |
| NCBI Gene Id | 983 |
| Protein Name | Cyclin-dependent kinase 1 |
| Description of Target | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P06493 |
| Protein Accession # | NP_001777.1 |
| Nucleotide Accession # | NM_001786.4 |
| Molecular Weight | 34 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CDK1 Antibody (Phospho-Thr14) (OAAN02724)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "CDK1 Antibody (Phospho-Thr14) (OAAN02724)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "CDK1 Antibody (Phospho-Thr14) (OAAN02724)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CDK1 Antibody (Phospho-Thr14) (OAAN02724)"?
This target may also be called "CDC2, CDC28A, P34CDC2" in publications.
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What is the shipping cost for "CDK1 Antibody (Phospho-Thr14) (OAAN02724)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CDK1 Antibody (Phospho-Thr14) (OAAN02724)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CDK1 Antibody (Phospho-Thr14) (OAAN02724)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "34 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CDK1 Antibody (Phospho-Thr14) (OAAN02724)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CDK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CDK1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CDK1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CDK1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CDK1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CDK1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
