CDH5 Recombinant Protein (OPCD02072)

Catalog No: OPCD02072

CDH5 Recombinant Protein (OPCD02072) using SDS-PAGE

CDH5 Recombinant Protein (OPCD02072) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly67-Gly390
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: >95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Cdh5
• Gene Full Name: cadherin 5
• Alias Symbols: 7B4;7B4/cadherin-5;AA408225;cadherin-5;Cd144;vascular endothelial cadherin;VE;Vec;VE-C;VEcad;VE-Cad;VE-cadherin;VECD.
• NCBI Gene Id: 12562
• Protein Name: Cadherin-5
• Description of Target: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
• Uniprot ID: P55284
• Protein Accession #: NP_033998.2
• Nucleotide Accession #: NM_009868.4
• Protein Size (# AA): Gly67~Gly390
• Molecular Weight: 40kDa