CDH5 Antibody (OABF00315)

Catalog No: OABF00315

Size:100UL

Formalin-fixed and frozen-OCT embedded mouse liver labeled with Rabbit Anti-VE Cadherin Polyclonal Antibody, Unconjugated (OABF00315) 1:100, overnight at 4C, The secondary antibody was diluted to 1:100 for 120 minutes at 37C.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
• Additional Information: Subcellular location: Cytoplasm
• Reconstitution and Storage: -20°C
• Immunogen: KLH conjugated synthetic peptide derived from mouse vascular endothelial cadherin
• Purification: Protein A Purified
• Concentration: 1 ug/ul
• Application Info: WB: 1:100 - 1000
  FC: 1:20 - 100
  IHC-P: : 1:100 - 500

Target Info

• Gene Symbol: Cdh5
• Gene Full Name: cadherin 5
• Alias Symbols: 7B4;7B4/cadherin-5;AA408225;cadherin-5;Cd144;vascular endothelial cadherin;VE;Vec;VE-C;VEcad;VE-Cad;VE-cadherin;VECD.
• NCBI Gene Id: 12562
• Protein Name: Cadherin-5
• Description of Target: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
• Uniprot ID: P55284