CDCA7 Antibody - N-terminal region (ARP66756_P050)

Catalog No: ARP66756_P050

Host: Rabbit
Target Name: CDCA7
Sample Type: MCF7 Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDCA7
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: CRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSE
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CDCA7 (ARP66756_P050) antibody is Catalog # AAP66756
• Publications:

  Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence. J Exp Med. 211, 2411-23 (2014). 25385755

Target Info

• Gene Symbol: CDCA7
• Gene Full Name: cell division cycle associated 7
• Alias Symbols: ICF3, JPO1
• NCBI Gene Id: 83879
• Protein Name: Cell division cycle-associated protein 7
• Description of Target: This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Uniprot ID: Q9BWT1-4
• Protein Size (# AA): 207
• Molecular Weight: 22kDa
• Protein Interactions: APP; UBC; tat;