CDC42EP5 Antibody - N-terminal region (OASG01418)

Catalog No: OASG01418

Size:100 uL

Western Blot using Jurkat

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human Cdc42EP5. Location: 1-80aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: Cdc42EP5 Polyclonal Antibody detects endogenous levels of Cdc42EP5 protein.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Target Info

• Gene Symbol: CDC42EP5
• Gene Full Name: CDC42 effector protein (Rho GTPase binding) 5
• Alias Symbols: CEP5, Borg3
• NCBI Gene Id: 148170; 58804;
• Description of Target: Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts
• Uniprot ID: Q6NZY7, Q9Z0X0
• Molecular Weight: 22 kDa