CDC42EP5 Antibody - middle region (ARP52797_P050)

Catalog No: ARP52797_P050

WB Suggested Anti-CDC42EP5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC42EP5
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Human: 100%; Mouse: 100%; Rat: 93%
• Peptide Sequence: Synthetic peptide located within the following region: HVGRGGDAFGDTSFLSRHGGGPPPEPRAPPAGAPRSPPPPAVPQSAAPSP
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-CDC42EP5 (ARP52797_P050) antibody is Catalog # AAP52797 (Previous Catalog # AAPP33809)
• Reference: Joberty,G., (2001) Nat. Cell Biol. 3 (10), 861-866

Target Info

• Gene Symbol: CDC42EP5
• Gene Full Name: CDC42 effector protein (Rho GTPase binding) 5
• Alias Symbols: CEP5, Borg3
• NCBI Gene Id: 148170
• Protein Name: Cdc42 effector protein 5
• Description of Target: CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.
• Uniprot ID: Q6NZY7
• Protein Accession #: NP_659494
• Nucleotide Accession #: NM_145057
• Protein Size (# AA): 148
• Molecular Weight: 15kDa
• Protein Interactions: SEPT7; CDC42; Sept6; Sept2;