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Catalog No: ARP42204_P050
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ARP42204_P050
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Datasheets/ManualsPrintable datasheet for anti-CD8B (ARP42204_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rat, Dog, Guinea Pig, Horse
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human CD8B
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Rat: 86%
Peptide SequenceSynthetic peptide located within the following region: RIYWLRQRQAPSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFI
Concentration0.5 mg/ml
Blocking PeptideFor anti-CD8B (ARP42204_P050) antibody is Catalog # AAP42204 (Previous Catalog # AAPP24627)
ReferenceMoody,A.M., (2003) J. Biol. Chem. 278 (9), 7240-7246
Gene SymbolCD8B
Gene Full NameCD8b molecule
Alias SymbolsLY3, P37, LEU2, LYT3, CD8B1
NCBI Gene Id926
Protein NamePutative uncharacterized protein CD8B1 EMBL AAY24019.1
Description of TargetThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
Uniprot IDQ53QL8
Protein Accession #NP_742097
Nucleotide Accession #NM_172099
Protein Size (# AA)246
Molecular Weight27kDa
Protein InteractionsELAVL1; CD8A; CD3D; CD8B; ST3GAL4; LCK;
  1. What is the species homology for "CD8B Antibody - N-terminal region (ARP42204_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rat, Dog, Guinea Pig, Horse".

  2. How long will it take to receive "CD8B Antibody - N-terminal region (ARP42204_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CD8B Antibody - N-terminal region (ARP42204_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CD8B Antibody - N-terminal region (ARP42204_P050)"?

    This target may also be called "LY3, P37, LEU2, LYT3, CD8B1" in publications.

  5. What is the shipping cost for "CD8B Antibody - N-terminal region (ARP42204_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CD8B Antibody - N-terminal region (ARP42204_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CD8B Antibody - N-terminal region (ARP42204_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "27kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CD8B Antibody - N-terminal region (ARP42204_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CD8B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CD8B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CD8B"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CD8B"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CD8B"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CD8B"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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