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Catalog No: OATA00146
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OATA00146
Availability: Discontinued
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for OATA00146
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityAfrican Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Pigtailed Macaque, Sooty Mangabey
Product FormatLiquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, pH 7.2
ClonalityMonoclonal
CloneSK1
IsotypeMouse IgG1, kappa
HostMouse
ConjugationBiotin
ApplicationFC
Reconstitution and Storage2-8C protected from light
SpecificityCD8
Application InfoThis antibody preparation has been quality-tested for flow cytometry using an appropriate cell type (as indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
Reference

Campanelli R, Palermo B, Garbelli S, Mantovani S, Lucchi P, Necker A, Lantelme E and Giachino C. 2002. Int Immunol. 14(1): 39-44. (Flow Cytometry)

Walter S, Herrgen L, Schoor O, Jung G, Wernet D, Buhring H-J, Rammensee H-G and Stevanovic S. 2003. J. Immunol. 171(10): 4974-4978. (Flow Cytometry)

Cervasi B, Paiardinin M, Serafini S, Fraternale A, Menotta M, Engram J, Lawson B, Staprans I, Piedimonte G, Perno CF, Silvestri G and Magnani M. 2006. J. Virol. 80(21): 10335-10345. (Flow Cytometry - Sooty Mangabeys)

Verstrepen BE, Verschoor EJ, Fagrouch ZC, Mooij P, de Groot NG, Bontrop RE, Bogers WM, Heeney JL and Koopman G. 2014. PLoS ONE 9(4): e95103. doi:10.1371/journal.pone.0095103. (Flow Cytometry - Chimpanzee)

Permar SR, Klumpp SA, Mansfield KG, Kim W-K, Gorgone DA, Lifton MA, Williams KC, Schmitz JE, Reimann KA, Axthelm MK, Polack FP, Griffin DE and Letvin NL. 2003. J. Virol. 77(7): 4396-4400. (Flow Cytometry - Rhesus)

Ahmed AFK, Ohtani H, Nio M, Fuanki N, Shimaoka S, Nagura H and Ohi R. 2001. J. Pathol. 193(3): 383-389. (Immunohistochemistry)

Bukowska-Straková K, Baran J, Gawlicka M and Kowalczyk, D. 2006. Folia Histochemica et Cytobiologica 44(3): 179-183.

Gene SymbolCD8A
Gene Full NameCD8a molecule
Alias SymbolsCD8, p32, Leu2
NCBI Gene Id925
Protein NameT-cell surface glycoprotein CD8 alpha chain
Description of TargetThe CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Uniprot IDP01732
Protein Accession #NP_001139345.1
Nucleotide Accession #NM_001145873.1
  1. What is the species homology for "CD8A Antibody : Biotin (OATA00146)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "African Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Pigtailed Macaque, Sooty Mangabey".

  2. How long will it take to receive "CD8A Antibody : Biotin (OATA00146)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "CD8A Antibody : Biotin (OATA00146)" provided in?

    This item is provided in "Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, pH 7.2".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CD8A Antibody : Biotin (OATA00146)"?

    This target may also be called "CD8, p32, Leu2" in publications.

  5. What is the shipping cost for "CD8A Antibody : Biotin (OATA00146)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "CD8A Antibody : Biotin (OATA00146)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CD8A Antibody : Biotin (OATA00146)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CD8A Antibody : Biotin (OATA00146)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CD8A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CD8A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CD8A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CD8A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CD8A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CD8A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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