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Datasheets/Manuals | Printable datasheet for CD81 Antibody (OAEE00320) (OAEE00320) |
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Predicted Species Reactivity | Cat|Human|Rabbit |
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Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Clonality | Monoclonal |
Clone | M38 |
Isotype | IgG1 |
Host | Mouse |
Application | Flow cytometry|Immunocytochemistry|Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | MOLT-4 (human T-ALL cell line) |
Purification | Purified |
Concentration | 1 mg/ml |
Specificity | The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells. |
Purity | > 95% (by SDS-PAGE) |
Application Info | FC: 1 ug/mL. In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines. |
Reference | Stehlíková O, Chovancová J, Tichý B, Krejčí M, Brychtová Y, Panovská A, Francová Skuhrová H, Burčková K, Borský M, Loja T, Mayer J, Pospíšilová S, Doubek M: Detecting minimal residual disease in patients with chronic lymphocytic leukemia using 8-color flow cytometry protocol in routine hematological practice. Int J Lab Hematol. 2013 Sep 13. doi: 10.1111/ijlh.12149. Fukudome K, Furuse M, Imai T, Nishimura M, Takagi S, Hinuma Y, Yoshie O: Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen in HTLV-1-positive T cells. J Virol. 1992 Mar;66(3):1394-401. Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ: Selective enrichment of tetraspan proteins on the internal vesicles ofmultivesicular endosomes and on exosomes secreted by human B-lymphocytes. J Biol Chem. 1998 Aug 7;273(32):20121-7." Imai T, Kakizaki M, Nishimura M, Yoshie O: Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82. J Immunol. 1995 Aug 1;155(3):1229-39. Imai T, Yoshie O: C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells. J Immunol. 1993 Dec 1;151(11):6470-81. |
Gene Symbol | CD81 |
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Gene Full Name | CD81 molecule |
Alias Symbols | 26 kDa cell surface protein TAPA-1;CD81 antigen;CD81 antigen (target of antiproliferative antibody 1);CVID6;S5.7;TAPA1;Target of the antiproliferative antibody 1;tetraspanin-28;tspan-28;TSPAN28. |
NCBI Gene Id | 975 |
Protein Name | CD81 antigen |
Description of Target | May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV. |
Uniprot ID | P60033 |
Protein Accession # | NP_001284578.1; NP_004347.1 |
Nucleotide Accession # | NM_001297649.1; NM_004356.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CD81 Antibody (OAEE00320)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Cat|Human|Rabbit".
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How long will it take to receive "CD81 Antibody (OAEE00320)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "CD81 Antibody (OAEE00320)" provided in?
This item is provided in "Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CD81 Antibody (OAEE00320)"?
This target may also be called "26 kDa cell surface protein TAPA-1;CD81 antigen;CD81 antigen (target of antiproliferative antibody 1);CVID6;S5.7;TAPA1;Target of the antiproliferative antibody 1;tetraspanin-28;tspan-28;TSPAN28." in publications.
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What is the shipping cost for "CD81 Antibody (OAEE00320)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CD81 Antibody (OAEE00320)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CD81 Antibody (OAEE00320)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CD81 Antibody (OAEE00320)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CD81"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CD81"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CD81"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CD81"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CD81"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CD81"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.