CD80 Antibody (OABF00934)

Catalog No: OABF00934

Size:100UL

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Western blot
• Additional Information: Subcellular location: Cytoplasm
• Reconstitution and Storage: -20°C
• Immunogen: KLH conjugated synthetic peptide derived from rat CD80
• Purification: Protein A Purified
• Concentration: 1 ug/ul
• Application Info: WB: 1:300-1000
  IHC-P: 1:200-400
  Fluorescent (IHC-P): 1:50-200
  Optimal dilutions should be determined by the end user.

Target Info

• Gene Symbol: Cd80
• Gene Full Name: Cd80 molecule
• Alias Symbols: B7-1;Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1);CD80 antigen;CD80-like;T-lymphocyte activation antigen CD80.
• NCBI Gene Id: 25408
• Protein Name: CD80 antigen, isoform CRA_a
• Description of Target: CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.
• Uniprot ID: G3V671