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CD80 Antibody (OABF00934)

100 ul
$359.00
In Stock
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Conjugation Options

OABF00934-FITC Conjugated

OABF00934-HRP Conjugated

OABF00934-Biotin Conjugated

Predicted Species Reactivity:
Mouse, Rat
Product Format:
Liquid. Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Conjugation:
Unconjugated
Application:
WB, IHC-P, Fluorescent-IHC
Additional Information:
Subcellular location: Cytoplasm
Reconstitution and Storage:
Store at -20°C for 12 months.
Replacement Item:
This antibody may replace item sc-115617 from Santa Cruz Biotechnology.
Immunogen:
KLH conjugated synthetic peptide derived between 270-321 aa from rat CD80.
Purification:
Purified by Protein A
Concentration:
1 ug/ul
Datasheets/Manuals:
Printable datasheet for OABF00934
Application Info:
WB: 1:300-1000
IHC-P: 1:200-400
Fluorescent (IHC-P): 1:50-200
Optimal dilutions should be determined by the end user.
Gene Symbol:
CD80
Official Gene Full Name:
Cd80 molecule
Alias Symbols:
B7-1; Activation B7 1 antigen; Activation B71 antigen; B lymphocyte activation antigen B7; B7; BB1; CD 80; CD28 antigen ligand 1 B7 1 antigen; CD28 antigen ligand 1 B71 antigen; CD28LG; CD28LG1; CD80 antigen; CD80 antigen precursor;CD80 molecule; Cost
NCBI Gene Id:
25408
Description of Target:
CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.
Swissprot Id:
G3V671
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express CD80.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express CD80.

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