CD80 Antibody : FITC (OABF00934-FITC)

Catalog No: OABF00934-FITC

Size:100ul

Product Info

• Predicted Species Reactivity: Mouse, Rat
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB, IHC-P, IF
• Additional Information: Subcellular location: Cytoplasm
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: KLH conjugated synthetic peptide derived from rat CD80
• Purification: Purified by Protein A.
• Concentration: 1 mg/ml
• Application Info: WB(1:100-1000)
  IHC-P(1:100-500)
  IF(1:50-200)

Target Info

• Gene Symbol: CD80
• Gene Full Name: Cd80 molecule
• Alias Symbols: B7-1
• NCBI Gene Id: 25408
• Description of Target: CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.