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- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for CD74 Antibody (OAEE00498) (OAEE00498) |
|---|
| Predicted Species Reactivity | Mouse |
|---|---|
| Product Format | Phosphate buffered saline (PBS), pH 7.4 |
| Clonality | Monoclonal |
| Clone | M5/114 |
| Isotype | IgG2b |
| Host | Rat |
| Application | Flow cytometry|Functional assay|Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot |
| Reconstitution and Storage | 2°C to 8°C |
| Immunogen | Activated C57BL/6 mouse spleen cells |
| Purification | Purified |
| Concentration | 1 mg/ml |
| Specificity | The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes. |
| Purity | > 95% (SDS-PAGE) |
| Application Info | FC: 2 ug/mL |
| Gene Symbol | CD74 |
|---|---|
| Gene Full Name | HLA class II histocompatibility antigen gamma chain |
| Alias Symbols | II, p33, DHLAG, HLADG, Ia-GAMMA |
| NCBI Gene Id | 972 |
| Protein Name | HLA class II histocompatibility antigen gamma chain |
| Description of Target | MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long. |
| Uniprot ID | P04233 |
| Protein Accession # | NP_001020329.1; NP_001020330.1; NP_004346.1 |
| Nucleotide Accession # | NM_001025158.2; NM_001025159.2; NM_004355.3 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "CD74 Antibody (OAEE00498)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".
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How long will it take to receive "CD74 Antibody (OAEE00498)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "CD74 Antibody (OAEE00498)" provided in?
This item is provided in "Phosphate buffered saline (PBS), pH 7.4".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "CD74 Antibody (OAEE00498)"?
This target may also be called "II, p33, DHLAG, HLADG, Ia-GAMMA" in publications.
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What is the shipping cost for "CD74 Antibody (OAEE00498)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "CD74 Antibody (OAEE00498)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "CD74 Antibody (OAEE00498)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "CD74 Antibody (OAEE00498)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CD74"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CD74"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CD74"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CD74"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CD74"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CD74"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
