CD5 Antibody (OAEE00266)

Catalog No: OAEE00266

Size:100UG

Flow Cytometry analysis of human Peripheral Blood Lymphocytes (PBL) stained with CRIS1 antibody (dilution of purified antibody 1 ug/ml); Fig. 1a Histogram - gated on lymphocytes, overlay with isotypic control (mouse IgG2a); Fig. 1b Dot plot.

Flow Cytometry analysis of human Peripheral Blood Lymphocytes (PBL) stained with CRIS1 antibody (dilution of purified antibody 1 ug/ml); Fig. 1a Histogram - gated on lymphocytes, overlay with isotypic control (mouse IgG2a); Fig. 1b Dot plot.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Clonality: Monoclonal
• Clone: CRIS1
• Isotype: IgG2a
• Host: Mouse
• Application: Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry-Frozen|Immunoprecipitation|Western blot
• Reconstitution and Storage: 2°C to 8°C
• Immunogen: stimulated human leukocytes
• Purification: Purified
• Concentration: 1 mg/ml
• Specificity: The antibody CRIS1 reacts with the cell surface glycoprotein CD5, a 67kDa single-chain transmembrane glycoprotein expressed on mature T lymphocytes, most of thymocytes and B lymphocytes subset (B-1a lymphocytes).
  HLDA I; WS Code T 29
  HLDA III; WS Code T 530
• Formulation: Purified
• Purity: > 95% (by SDS-PAGE)
• Storage Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Reference: Guarne A, Bravo J, Calvo J, Lozano F, Vives J, Fita I: Conformation of the hypervariable region L3 without the key proline residue. Protein Sci. 1996 Jan;5(1):167-9.
  Alberola-Ila J, Places L, Cantrell DA, Vives J, Lozano F: Intracellular events involved in CD5-induced human T cell activation and proliferation. J Immunol. 1992 Mar 1;148(5):1287-93.
  Arrizabalaga P, Mirapeix E, Darnell A, Torras A, Revert L: Cellular immunity analysis using monoclonal antibodies in human glomerulonephritis. Nephron. 1989;53(1):41-9.
  Leukocyte Typing III., McMichael A. J. et al. (Eds.), Oxford University Press (1987).
  Raman C: CD5, an important regulator of lymphocyte selection and immune tolerance. Immunol Res. 2002;26(1-3):255-63.
  Freedman AS, Freeman G, Whitman J, Segil J, Daley J, Levine H, Nadler LM: Expression and regulation of CD5 on in vitro activated human B cells. Eur J Immunol. 1989 May;19(5):849-55.

Target Info

• Gene Symbol: CD5
• Gene Full Name: CD5 molecule
• Alias Symbols: CD5 antigen (p56-62);epididymis secretory sperm binding protein;LEU1;lymphocyte antigen T1/Leu-1;T1;T-cell surface glycoprotein CD5.
• NCBI Gene Id: 921
• Protein Name: T-cell surface glycoprotein CD5
• Description of Target: May act as a receptor in regulating T-cell proliferation.
• Uniprot ID: P06127
• Protein Accession #: NP_055022.2
• Nucleotide Accession #: NM_014207.3