CD47 Recombinant Protein (OPCD04064)

Catalog No: OPCD04064

CD47 Recombinant Protein (OPCD04064) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Ctrl (+), SDS-PAGE, WB
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala18-Gly219
  Subcellular Location: Cell membrane; Multi-pass membrane prote
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Cd47
• Gene Full Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
• Alias Symbols: 9130415E20Rik;AA407862;AI848868;AW108519;B430305P08Rik;IAP;integrin-associated protein;It;Itgp;leukocyte surface antigen CD47;Rh-related antigen.
• NCBI Gene Id: 16423
• Protein Name: Leukocyte surface antigen CD47
• Description of Target: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection (By similarity).
• Uniprot ID: Q61735
• Protein Accession #: NP_034711.1
• Nucleotide Accession #: NM_010581.3
• Protein Size (# AA): Ala18~Gly219
• Molecular Weight: 23kDa